Invention Grant
- Patent Title: Process and materials for the rapid detection of Streptococcus pneumoniae employing purified antigen-specific antibodies
- Patent Title (中): 使用纯化的抗原特异性抗体快速检测肺炎链球菌的方法和材料
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Application No.: US14628827Application Date: 2015-02-23
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Publication No.: US09310369B2Publication Date: 2016-04-12
- Inventor: Norman J. Moore , Mary K. Konstantin , Vladimir A. Koulchin , Elena V. Molokova
- Applicant: Alere Scarborough, Inc.
- Applicant Address: US ME Scarborough
- Assignee: Alere Scarborough, Inc.
- Current Assignee: Alere Scarborough, Inc.
- Current Assignee Address: US ME Scarborough
- Agency: Foley Hoag LLP
- Main IPC: G01N33/558
- IPC: G01N33/558 ; G01N33/569 ; C07K16/12
Abstract:
Disclosed is a cell wall C-polysaccharide antigen of Streptococcus pneumoniae which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1N Na OH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against Streptococcus pneumoniae which have been affinity purified by passing them over a chromatographic affinity matrix to which is coupled the purified and at least partially deproteinized antigen to render them antigen-specific.
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