Invention Grant
US09314339B2 Implants for replacing cartilage, with negatively-charged hydrogel surfaces and flexible matrix reinforcement
有权
用于替代软骨的植入物,具有带负电荷的水凝胶表面和柔性基质增强
- Patent Title: Implants for replacing cartilage, with negatively-charged hydrogel surfaces and flexible matrix reinforcement
- Patent Title (中): 用于替代软骨的植入物,具有带负电荷的水凝胶表面和柔性基质增强
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Application No.: US10677444Application Date: 2003-10-02
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Publication No.: US09314339B2Publication Date: 2016-04-19
- Inventor: Kevin A. Mansmann
- Applicant: Kevin A. Mansmann
- Applicant Address: US PA Paoli
- Assignee: Formae, Inc.
- Current Assignee: Formae, Inc.
- Current Assignee Address: US PA Paoli
- Agency: Duane Morris LLP
- Main IPC: A61F2/08
- IPC: A61F2/08 ; A61F2/30 ; A61L27/44 ; A61L27/50 ; A61L27/52 ; A61L27/56 ; A61F2/50 ; A61F2/38 ; A61F2/40 ; A61F2/42 ; A61F2/46

Abstract:
A permanent non-resorbable implant allows surgical replacement of cartilage in articulating joints, using a hydrogel material (such as a synthetic polyacrylonitrile polymer) reinforced by a flexible fibrous matrix. Articulating hydrogel surface(s) are chemically treated to provide a negative electrical charge that emulates the negative charge of natural cartilage, and also can be treated with halogenating, cross-linking, or other chemical agents for greater strength. For meniscal-type implants, the reinforcing matrix can extend out from the peripheral rim of the hydrogel, to allow secure anchoring to soft tissue such as a joint capsule. For bone-anchored implants, a porous anchoring layer enables tissue ingrowth, and a non-planer perforated layer can provide a supportive interface between the hard anchoring material and the softer hydrogel material.
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