Invention Grant
- Patent Title: Compositions and methods for increasing dextromethorphan plasma levels and related pharmacodynamic effects
- Patent Title (中): 增加右美沙芬血浆水平和相关药效学作用的组合物和方法
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Application No.: US14878998Application Date: 2015-10-08
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Publication No.: US09314462B2Publication Date: 2016-04-19
- Inventor: Herriot Tabuteau
- Applicant: ANTECIP BIOVENTURES II LLC
- Applicant Address: US NY New York
- Assignee: ANTECIP BIOVENTURES II LLC
- Current Assignee: ANTECIP BIOVENTURES II LLC
- Current Assignee Address: US NY New York
- Agency: K&L Gates LLP
- Agent Brent A. Johnson; Louis C. Cullman
- Main IPC: A61K31/137
- IPC: A61K31/137 ; A61K31/485 ; A61K31/4748

Abstract:
This disclosure relates to methods of increasing dextromethorphan plasma levels comprising co-administering hydroxybupropion, or a prodrug thereof, and dextromethorphan to a human being in need of treatment with dextromethorphan. Dosage forms, drug delivery systems, and methods related to dextromethorphan and hydroxybupropion or a prodrug of bupropion are also disclosed.
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