Invention Grant
US09314478B2 Method of making an anhydrous, fat soluble, chewable drug delivery formulation
有权
制备无水,脂溶性,咀嚼药物递送制剂的方法
- Patent Title: Method of making an anhydrous, fat soluble, chewable drug delivery formulation
- Patent Title (中): 制备无水,脂溶性,咀嚼药物递送制剂的方法
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Application No.: US14656667Application Date: 2015-03-12
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Publication No.: US09314478B2Publication Date: 2016-04-19
- Inventor: Douglas Robert Cleverly , David Anthony Gill , Keryn Davies , Priyanka Agarwal , Su Win , Gopinath Devaraj
- Applicant: Argenta Manufacturing Limited
- Applicant Address: NZ Aukland
- Assignee: Argenta Manufacturing Limited
- Current Assignee: Argenta Manufacturing Limited
- Current Assignee Address: NZ Aukland
- Agency: Polsinelli PC
- Agent Tracey S. Truitt
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K9/68 ; A61K31/7048 ; A61K9/00 ; A61K9/14 ; A23K1/00 ; A23K1/16 ; A23K1/18 ; A61K9/50 ; A61K31/138 ; A61K31/166 ; A61K31/35 ; A61K31/404 ; A61K31/4184 ; A61K31/4985 ; A61K31/506 ; A61K31/5415 ; A61K31/573 ; A23K1/165 ; A23K1/17

Abstract:
The present invention relates to a chewable formulation for delivering a nutritional or pharmaceutically active agent to an animal target. The chewable formulation comprises a nutritional ingredient or an effective amount of a pharmaceutically active agent, and a plasticizer. The chewable formulation is formed by extrusion and the formulation contains substantially no unbound water, nor is any water added in the manufacturing process. The present invention also relates to a method of manufacturing a shelf stable chewable formulation which comprises mixing the nutritional or pharmaceutically active agent with a fat, lipid or fat and lipid to obtain a first composition, adding one or more plasticizers to the first mixture to obtain a second composition, extruding the second composition at a temperature sufficient to melt the fat and lipid, and allowing the extruded second composition to cool to room temperature thereby providing the chewable formulation.
Public/Granted literature
- US20150190417A1 CHEWABLE FORMULATION Public/Granted day:2015-07-09
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