Invention Grant
- Patent Title: Bacteriocin derived from Lactobacillus rhamnosus
- Patent Title (中): 源自鼠李糖乳杆菌的细菌素
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Application No.: US14707956Application Date: 2015-05-08
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Publication No.: US09314498B2Publication Date: 2016-04-19
- Inventor: Hiroki Nikawa
- Applicant: Hiroshima University
- Applicant Address: JP Hiroshima
- Assignee: Hiroshima University
- Current Assignee: Hiroshima University
- Current Assignee Address: JP Hiroshima
- Agency: K&L Gates, LLP
- Agent Louis Cullman; Michelle Glasky Bergman
- Priority: JP2011-027882 20110210; JP2011-184655 20110826
- Main IPC: A61K38/16
- IPC: A61K38/16 ; C07K14/335 ; C12P21/02 ; C12R1/225

Abstract:
Provided is a bacteriocin that is capable of being easily mass-produced, has high antimicrobial activity even at low concentration, has a wide antimicrobial spectrum, and is less likely to produce resistant microorganisms. The bacteriocin has the amino acid sequence shown in SEQ ID NO: 1 or SEQ ID NO: 2 in SEQUENCE LISTING, or has the same amino acid sequence as shown in SEQ ID NO: 1 or SEQ ID NO: 2 in SEQUENCE LISTING except that one or several amino acids are deleted, substituted, inserted and/or added, wherein the amino acid sequence provides antimicrobial activity and the isoelectric point is not less than 12.
Public/Granted literature
- US20150238565A1 Bacteriocin Derived from Lactobacillus rhamnosus Public/Granted day:2015-08-27
Information query
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