Invention Grant
US09314536B2 Compounds and methods for the treatment of EGFR positive diseases
有权
用于治疗EGFR阳性疾病的化合物和方法
- Patent Title: Compounds and methods for the treatment of EGFR positive diseases
- Patent Title (中): 用于治疗EGFR阳性疾病的化合物和方法
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Application No.: US13835537Application Date: 2013-03-15
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Publication No.: US09314536B2Publication Date: 2016-04-19
- Inventor: Chao Qin , Shengfeng Li
- Applicant: Bio-Thera Solutions, Ltd., Co.
- Applicant Address: CN Science City
- Assignee: Bio-Thera Solutions, Ltd., Co.
- Current Assignee: Bio-Thera Solutions, Ltd., Co.
- Current Assignee Address: CN Science City
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: CN201210564074 20121221; CN201310081764 20130314
- Main IPC: C07K17/06
- IPC: C07K17/06 ; C07K16/18 ; A61K47/48 ; C07D498/14

Abstract:
Disclosed herein are anti-EGFR antibodies conjugated with maytansinoid drugs for targeted delivery to disease tissues. Methods related to the preparation and uses of such antibody drug conjugates to treat EGFR positive cells in cancers are provided.
Public/Granted literature
- US20140178412A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF EGFR POSITIVE DISEASES Public/Granted day:2014-06-26
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