Invention Grant
- Patent Title: Human artificial chromosome vector
- Patent Title (中): 人类人造染色体载体
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Application No.: US13510327Application Date: 2010-11-17
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Publication No.: US09315824B2Publication Date: 2016-04-19
- Inventor: Yoshimi Kuroiwa , Hiroaki Matsushita , Akiko Sano
- Applicant: Yoshimi Kuroiwa , Hiroaki Matsushita , Akiko Sano
- Applicant Address: US SD Sioux Falls
- Assignee: SAB, LLC
- Current Assignee: SAB, LLC
- Current Assignee Address: US SD Sioux Falls
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/JP2010/070514 WO 20101117
- International Announcement: WO2011/062207 WO 20110526
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C07H21/02 ; C12P21/00 ; A01K67/027 ; C12N15/85 ; C07K16/00 ; C07K16/12
Abstract:
The present invention provides a human artificial chromosome vector comprising a gene encoding the human antibody heavy chain, a gene encoding the human antibody light chain, and a gene encoding IgM heavy chain constant region derived from a nonhuman animal; and being capable of producing a human antibody with a higher efficiency when the vector is introduced into an animal. By immunizing the animal produced using a human artificial chromosome vector of the present invention with a desired antigen, a large quantity of human polyclonal antibodies can be supplied.
Public/Granted literature
- US20120222140A1 HUMAN ARTIFICIAL CHROMOSOME VECTOR Public/Granted day:2012-08-30
Information query
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