LED lighting device and LED control system are provided. An LED lighting device includes an LED power supply unit, a controller unit, a microphone module, a wireless communication module, and an LED light source assembly. An LED control system includes at least one LED lighting device, at least one of a smart terminal and a cloud server, and at least one smart home appliance. When a user sends a voice command to the LED lighting device, the LED lighting device captures and processes signal data from the voice command to provide control data to the smart terminal or cloud server, which then recognizes and processes the control data to provide processed control data. The processed control data are then sent to a corresponding smart home appliance communicated with the smart terminal or the cloud server to control an operation of the smart home appliance.