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Invention Grant
US09320729B2 Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative 有权
包含（1r，4r）-6'-氟 - N，N-二甲基-4-苯基-4'，9'-二氢-3'H-螺[环己烷-1,1'-吡喃并[ 4，b]吲哚] -4-胺和丙酸衍生物

Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
Abstract:
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient, which is selected from (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and the physiologically acceptable salts thereof, and a second pharmacologically active ingredient, which is a propionic acid derivative selected from the group consisting of ibuprofen, naproxen, ketoprofen, flurbiprofen, fenoprofen, fenbufen, suprofen, pirprofen, indoprofen, tiaprofenic acid, oxaprozin, ibuproxam, flunoxaprofen, alminoprofen, naproxcinod, and the physiologically acceptable salts thereof.
Abstract(Chinese):

本发明涉及包含第一药理活性成分的药物组合物，其选自（1r，4r）-6'-氟-N，N-二甲基-4-苯基-4'，9'-二氢-3'H - 螺[环己烷-1,1'-吡喃并[3,4，b]吲哚] -4-胺及其生理上可接受的盐，和第二药理活性成分，其是选自以下的丙酸衍生物： 布洛芬，萘普生，酮洛芬，氟比洛芬，非诺洛芬，芬布芬，依洛芬，吡柔芬，吲哚洛芬，噻吗啡酸，奥沙普秦，布洛康，氟诺洛芬，阿仑洛芬，萘普生和其生理学上可接受的盐。

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