Invention Grant
US09321208B2 Nanofibers with excellent biodegradability and biocompatibility and method for producing the same
有权
具有优异的生物降解性和生物相容性的纳米纤维及其制造方法
- Patent Title: Nanofibers with excellent biodegradability and biocompatibility and method for producing the same
- Patent Title (中): 具有优异的生物降解性和生物相容性的纳米纤维及其制造方法
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Application No.: US13819521Application Date: 2011-08-29
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Publication No.: US09321208B2Publication Date: 2016-04-26
- Inventor: Tsutomu Ono , Yukitaka Kimura
- Applicant: Tsutomu Ono , Yukitaka Kimura
- Applicant Address: JP Osaka
- Assignee: TMT Machinery, Inc.
- Current Assignee: TMT Machinery, Inc.
- Current Assignee Address: JP Osaka
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2010-192223 20100830
- International Application: PCT/JP2011/069439 WO 20110829
- International Announcement: WO2012/029710 WO 20120308
- Main IPC: A61K9/00
- IPC: A61K9/00 ; B29C47/00 ; D01D5/06 ; D01F6/84 ; D01F6/86

Abstract:
The invention provides a method for producing nanofibers of an aliphatic polyester resin (a biodegradable resin) with higher productivity than heretofore achieved, for example, without the need of cumbersome steps such as drawing and with operability at normal temperature. The method for producing nanofibers according to the invention includes (1) an extrusion step of extruding an organic solvent solution (S) into filaments in an aqueous solution (W) including a surfactant (SF) and water, the organic solvent solution (S) including an aliphatic polyester resin (A0) or an oil-soluble low block copolymer (A) including a block derived from an aliphatic polyester resin (A1) and a block derived from a hydrophilic polymer (A2), and an organic solvent (S1); and (2) a spinning step of collecting the filaments of the organic solvent solution (S) extruded in the step (1) while simultaneously diffusing or extracting the organic solvent (S1) of the organic solvent solution (S) into the aqueous solution (W), thereby forming fibers including the aliphatic polyester resin (A0) or the oil-soluble low block copolymer (A).
Public/Granted literature
- US20130157367A1 NANOFIBERS WITH EXCELLENT BIODEGRADABILITY AND BIOCOMPATIBILITY AND METHOD FOR PRODUCING THE SAME Public/Granted day:2013-06-20
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