Invention Grant
- Patent Title: Methods and use of bifunctional enzyme-building clamp-shaped molecules
- Patent Title (中): 双功能酶建立钳形分子的方法和用途
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Application No.: US14005066Application Date: 2012-03-16
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Publication No.: US09321759B2Publication Date: 2016-04-26
- Inventor: Mark I. Greene , Hongtao Zhang , Alan Berezov , Zheng Cai
- Applicant: Mark I. Greene , Hongtao Zhang , Alan Berezov , Zheng Cai
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2012/029410 WO 20120316
- International Announcement: WO2012/125913 WO 20120920
- Main IPC: C07D417/12
- IPC: C07D417/12 ; A61K31/497 ; A61K31/517 ; C07D239/94 ; C07D285/125
Abstract:
This invention is in the fields of cancer therapy. More particularly it concerns compounds which are useful agents for inhibiting cell proliferative disorders, especially those disorders characterized by over activity and/or inappropriate activity of a EGFR, including EGFR-related cancers, and methods for treating these disorders.
Public/Granted literature
- US20140309246A1 METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES Public/Granted day:2014-10-16
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