Invention Grant
US09321760B2 Aminopyrimidine derivatives for use as modulators of kinase activity
有权
用作激酶活性调节剂的氨基嘧啶衍生物
- Patent Title: Aminopyrimidine derivatives for use as modulators of kinase activity
- Patent Title (中): 用作激酶活性调节剂的氨基嘧啶衍生物
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Application No.: US14236405Application Date: 2012-09-12
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Publication No.: US09321760B2Publication Date: 2016-04-26
- Inventor: Ruoxi Lan , Bayard R. Huck , Xiaoling Chen , Lizbeth Celeste Deselm , Hui Qiu , Yufang Xiao , Constantin Neagu , Igor Mochalkin , Theresa L. Johnson
- Applicant: Ruoxi Lan , Bayard R. Huck , Xiaoling Chen , Lizbeth Celeste Deselm , Hui Qiu , Yufang Xiao , Constantin Neagu , Igor Mochalkin , Theresa L. Johnson
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: EMD Serono Reaserch and Development Institute
- Agent Dwight D. Kim
- International Application: PCT/US2012/054877 WO 20120912
- International Announcement: WO2013/040044 WO 20130321
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D417/12 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D403/06 ; C07D239/48 ; C07D413/04 ; C07D417/14 ; C07D405/12
Abstract:
The invention provides novel heterocyclic amine compounds according to Formula (I) and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Public/Granted literature
- US20150126484A1 AMINOPYRIMIDINE DERIVATIVES FOR USE AS MODULATORS OF KINASE ACTIVITY Public/Granted day:2015-05-07
Information query
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