Invention Grant
US09321795B2 Use of hydroxycinnamaldehyde glycoside derivatives for treating glomerulonephritis
有权
使用羟基肉桂醛糖苷衍生物治疗肾小球性肾炎
- Patent Title: Use of hydroxycinnamaldehyde glycoside derivatives for treating glomerulonephritis
- Patent Title (中): 使用羟基肉桂醛糖苷衍生物治疗肾小球性肾炎
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Application No.: US14693619Application Date: 2015-04-22
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Publication No.: US09321795B2Publication Date: 2016-04-26
- Inventor: Ann Chen , Shuk-Man Ka , Kuo-Feng Hua , Shui-Tein Chen , Kuo-Ping Chao
- Applicant: National Defense Medical Center
- Applicant Address: TW Taipei
- Assignee: National Defense Medical Center
- Current Assignee: National Defense Medical Center
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C., INTELLECTUAL PROPERTY ATTORNEYS
- Agent Anthony King
- Priority: TW103114584A 20140422
- Main IPC: C07H15/203
- IPC: C07H15/203 ; A61K31/7034 ; A61K45/06

Abstract:
The present invention relates to a new use of a cinnamaldehyde derivative of formula (I) for treating glomerulonephritis (GN). Particularly, the present invention discloses that the cinnamaldehyde derivative of formula (I) is effective in treating glomerulonephritis (GN), which can alleviate various symptoms and signs of GN, including reducing proteinuria, serum blood urea nitrogen (BUN), glomerular cell proliferation, and renal macrophage/lymphocyte infiltration, etc.
Public/Granted literature
- US20150299242A1 USE OF HYDROXYCINNAMALDEHYDE GLYCOSIDE DERIVATIVES FOR TREATING GLOMERULONEPHRITIS Public/Granted day:2015-10-22
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