Invention Grant
- Patent Title: Compositions and methods for treating bladder cancer
- Patent Title (中): 膀胱癌的组合物和方法
-
Application No.: US13502132Application Date: 2010-10-14
-
Publication No.: US09321820B2Publication Date: 2016-04-26
- Inventor: Thomas Flaig , Arthur E. Frankel , Andrew Thorburn , Michael L. Glode
- Applicant: Thomas Flaig , Arthur E. Frankel , Andrew Thorburn , Michael L. Glode
- Applicant Address: US CO Denver US TX Temple
- Assignee: The Regents of the University of Colorado,Scott & White Healthcare
- Current Assignee: The Regents of the University of Colorado,Scott & White Healthcare
- Current Assignee Address: US CO Denver US TX Temple
- Agency: Cochran Freund & Young, LLC
- Agent Michael T. Wiwchar
- International Application: PCT/US2010/052634 WO 20101014
- International Announcement: WO2011/047135 WO 20110421
- Main IPC: A61P13/10
- IPC: A61P13/10 ; A61K38/00 ; A61K38/18 ; C07K19/00 ; C07K14/485 ; C07K14/34 ; A61K38/16
Abstract:
The present invention provides methods and compositions for treating bladder cancer. In particular, the present invention provides a fusion protein comprising a toxin moiety that is linked to an epithelial growth factor (EGF) moiety. The toxin moiety and the EGF moiety can be linked optionally via a linker. Typically, the fusion protein is administered intravesically into the cancerous bladder.
Public/Granted literature
- US20120232010A1 Compositions and Methods for Treating Bladder Cancer Public/Granted day:2012-09-13
Information query
