Invention Grant
- Patent Title: Factor VIII variants having a decreased cellular uptake
- Patent Title (中): 因子VIII变体具有降低的细胞摄取
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Application No.: US13822942Application Date: 2011-09-14
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Publication No.: US09321827B2Publication Date: 2016-04-26
- Inventor: Henriet Meems , Alexander Benjamin Meijer , Koenraad Mertens , Ole Hvilsted Olsen , Kasper Lamberth , Peder Lisby Noerby , Laust Bruun Johnsen , Marianne Hjortnæs Kjalke , Henning Ralf Stennicke , Johannes Voorberg , Maartje Van Den Biggelaar
- Applicant: Henriet Meems , Alexander Benjamin Meijer , Koenraad Mertens , Ole Hvilsted Olsen , Kasper Lamberth , Peder Lisby Noerby , Laust Bruun Johnsen , Marianne Hjortnæs Kjalke , Henning Ralf Stennicke , Johannes Voorberg , Maartje Van Den Biggelaar
- Applicant Address: DK Bagsvaerd NL Amsterdam
- Assignee: Novo Nordisk A/S,Sanquin Blood Supply Foundation
- Current Assignee: Novo Nordisk A/S,Sanquin Blood Supply Foundation
- Current Assignee Address: DK Bagsvaerd NL Amsterdam
- Agent Nonna G. Akopyan
- Priority: EP10176731 20100915; EP11173768 20110713
- International Application: PCT/EP2011/065913 WO 20110914
- International Announcement: WO2012/035050 WO 20120322
- Main IPC: A61K38/37
- IPC: A61K38/37 ; C07K14/755 ; A61P7/00
Abstract:
The present invention relates to modified coagulation factors. In particular, the present invention relates to modied Factor VIII molecules having decreased cellular uptake.
Public/Granted literature
- US20140057848A1 FACTOR VIII VARIANTS HAVING A DECREASED CELLULAR UPTAKE Public/Granted day:2014-02-27
Information query
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