Invention Grant
- Patent Title: Antibodies immunoreactive with heregulin-coupled HER3
- Patent Title (中): 抗体与免疫球蛋白偶联的HER3免疫反应
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Application No.: US14475348Application Date: 2014-09-02
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Publication No.: US09321839B2Publication Date: 2016-04-26
- Inventor: Bruce Keyt , Lawrence M. Kauvar , Ellen J. Collarini , Orit Foord , Gizette Sperinde , Marjan Fatholahi , Hung Nguyen
- Applicant: Trellis Bioscience, LLC
- Applicant Address: US CA Menlo Park
- Assignee: TRELLIS BIOSCIENCE, LLC
- Current Assignee: TRELLIS BIOSCIENCE, LLC
- Current Assignee Address: US CA Menlo Park
- Agency: Morrison & Foerster LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K39/395 ; C07K16/28 ; C07K16/22 ; C07K16/30 ; C07K16/32 ; C07K16/40
Abstract:
Recombinant materials and methods for producing antibodies that specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer that expresses HER3.
Public/Granted literature
- US20140370548A1 ANTIBODIES IMMUNOREACTIVE WITH HEREGULIN-COUPLED HER3 Public/Granted day:2014-12-18
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