Invention Grant
US09321999B2 Compositions for increasing polypeptide stability and activity, and related methods
有权
用于增加多肽稳定性和活性的组合物及相关方法
- Patent Title: Compositions for increasing polypeptide stability and activity, and related methods
- Patent Title (中): 用于增加多肽稳定性和活性的组合物及相关方法
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Application No.: US12950349Application Date: 2010-11-19
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Publication No.: US09321999B2Publication Date: 2016-04-26
- Inventor: Olev Kahre , Kadri Artma , Tiina Kahre
- Applicant: Olev Kahre , Kadri Artma , Tiina Kahre
- Applicant Address: EE Tartu
- Assignee: SOLIS BIODYNE OÜ
- Current Assignee: SOLIS BIODYNE OÜ
- Current Assignee Address: EE Tartu
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12P21/04
- IPC: C12P21/04 ; C12N9/12 ; C07K14/435 ; C12N9/00 ; C07K14/00 ; C12N9/14 ; C12N9/22 ; C12N9/50 ; C12N9/78 ; C12N9/96

Abstract:
This disclosure provides peptides, polypeptides, fusion polypeptides, compositions, and methods for enhancing or increasing the stability of a polypeptide (e.g., Taq polymerase). Such peptides, polypeptides, fusion polypeptides, or compositions include polypeptides linked to a peptide tag that enhances the stability of the polypeptide. The peptides, polypeptides, fusion polypeptides, compositions may also enhance the activity, specificity, and/or fidelity of other polypeptides in a reaction mixture. The disclosure also provides methods of using such peptides, polypeptides, fusion polypeptides, compositions.
Public/Granted literature
- US20110142792A1 Compositions for Increasing Polypeptide Stability and Activity, and Related Methods Public/Granted day:2011-06-16
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