Provided are a textile fabric sheet having stain and liquid resistance including (a) a fabric substrate, (b) a first polyurethane coating layer formed on a first surface of the fabric substrate; (c) a second aqueous acrylic coating layer formed on the first coating layer of the polyurethane coating layer; and (d) a third stain-resistant coating layer formed on the second aqueous acrylic coating layer and a method of preparing the same. Thus, a texture characteristic of the fabric substrate itself can be exhibited, and due to the polyurethane coating layer, the aqueous acrylic coating layer and the stain-resistant coating layer stacked in three steps, excellent water resistance, stain resistance and air permeability can be exhibited.