Invention Grant
- Patent Title: Use of cannabinoid compounds for stimulating melanogenesis
- Patent Title (中): 使用大麻素化合物刺激黑素生成
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Application No.: US14237015Application Date: 2012-08-03
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Publication No.: US09326927B2Publication Date: 2016-05-03
- Inventor: Michela Zuccolo , Roland Jourdain , Lionel Breton , Mauro Maccarrone
- Applicant: Michela Zuccolo , Roland Jourdain , Lionel Breton , Mauro Maccarrone
- Applicant Address: FR Paris
- Assignee: L'OREAL
- Current Assignee: L'OREAL
- Current Assignee Address: FR Paris
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: FR1157213 20110805
- International Application: PCT/FR2012/051846 WO 20120803
- International Announcement: WO2013/021128 WO 20130214
- Main IPC: A61K8/42
- IPC: A61K8/42 ; A61Q5/10 ; A61Q19/04 ; A61K31/164 ; A61K31/16 ; A61Q5/00 ; A61Q19/00

Abstract:
The invention relates to the nontherapeutic cosmetic use of at least one cannabinoid compound chosen from the compounds corresponding to general formula (I): and also the geometric isomers and optical isomers thereof, the cosmetically acceptable acid or base salts thereof, and the hydrates thereof; in which compounds of formula (I): R1 represents a hydrogen atom or a C1-C30 alkyl group; it being possible for said alkyl group to be optionally substituted with a hydroxyl (OH) group; R2 represents a halogen atom or a group chosen from hydroxyl, thiol (SH), and amino optionally substituted with one or two C1-C6 alkyl groups; R3 and R4 form, together with the carbon atom which bears them, an oxo group or else R3 and R4 represent a hydrogen atom; R5 represents a hydrogen atom or a C1-C6 alkyl group; X represents a heteroatom chosen from oxygen and sulfur atoms and the divalent group —N(R6)—, with R6 representing a hydrogen atom or a C1-C6 alkyl group; represents a single or double bond; n is 1, 2 or 3, preferentially 1 or 2; it being understood that, when R3 and R4 together form an oxo group with the carbon atom which bears them and X represents an oxygen atom, then R1 cannot represent a hydroxymethyl group, as an agent for coloring keratin materials. It also relates to one of these specific cannabinoid compounds for use thereof in the treatment of vitiligo or pityriasis versicolor, to nontherapeutic cosmetic processes for coloring the skin or for treating canities, comprising the topical application to the skin and/or head hair, or the oral administration, of a composition comprising, in a physiologically acceptable medium, one of these cannabinoid compounds, and to a process for selecting an active agent which promotes the pigmentation of keratin materials.
Public/Granted literature
- US20140193349A1 USE OF CANNABINOID COMPOUNDS FOR STIMULATING MELANOGENESIS Public/Granted day:2014-07-10
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