Invention Grant
- Patent Title: Laminated tablet and manufacturing method therefor
- Patent Title (中): 层压片及其制造方法
-
Application No.: US14002451Application Date: 2012-03-02
-
Publication No.: US09326946B2Publication Date: 2016-05-03
- Inventor: Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
- Applicant: Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Foley & Lardner LLP
- Priority: JP2011-046617 20110303
- International Application: PCT/JP2012/055382 WO 20120302
- International Announcement: WO2012/118180 WO 20120907
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K9/24 ; A61K45/06

Abstract:
According to the present invention, a multilayer tablet showing suppressed layer separation and a production method thereof are provided. A concave portion having a depth of not less than 0.1 mm Ka is formed on at least one surface Sa of the both front and back surfaces (Sa, Sb) of a multilayer tablet. Particularly, a multilayer structure obtained by, in tableting, forming a convex portion for forming the concave portion on at least the upper punch, and preliminarily compressing all layers in the multilayer tablet with the upper punch to form a concave portion having the same shape with a depth of not less than 0.1 mm on the upper surface of all layers, wherein the powder materials of the next layer are protruding into the concave portion, is a preferable embodiment.
Public/Granted literature
- US20140023708A1 LAMINATED TABLET AND MANUFACTURING METHOD THEREFOR Public/Granted day:2014-01-23
Information query