Vehicles having internal body cavity seals and methods of assembling the same are disclosed herein. In one embodiment, a vehicle includes a vehicle structural member, an exterior vehicle body panel that is coupled to the vehicle structural member and is spaced apart from the vehicle structural member at an internal body cavity, and a compressible sealing member that is positioned in the internal body cavity such that the compressible sealing member is concealed from an exterior of the vehicle. The compressible sealing member is coupled to at least one of the vehicle structural member or the exterior vehicle body panel and is compressed from an uninstalled thickness such that the compressible sealing member contacts both the vehicle structural member and the exterior vehicle body panel.