Invention Grant
US09328073B2 Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors
有权
醇，二醇和碳水化合物取代的茚并异喹啉作为拓扑异构酶I抑制剂
- Patent Title: Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors
- Patent Title (中): 醇，二醇和碳水化合物取代的茚并异喹啉作为拓扑异构酶I抑制剂
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Application No.: US14119673Application Date: 2012-05-24
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Publication No.: US09328073B2Publication Date: 2016-05-03
- Inventor: Mark S. Cushman , Yves George Pommier
- Applicant: Mark S. Cushman , Yves George Pommier
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- International Application: PCT/US2012/039365 WO 20120524
- International Announcement: WO2012/162513 WO 20121129
- Main IPC: C07D221/18
- IPC: C07D221/18 ; C07D311/94
Abstract:
The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein RA, RD, W, X and Y are defined herein, pharmaceutical compositions and formulations comprising the indenoisoquinoline compounds, their synthesis, and methods for their use in the treatment and/or prevention of cancer.
Public/Granted literature
- US20150148370A1 ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS Public/Granted day:2015-05-28
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