Invention Grant
- Patent Title: Bicyclic PKM2 activators
- Patent Title (中): 双环PKM2激活剂
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Application No.: US13996286Application Date: 2011-12-21
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Publication No.: US09328077B2Publication Date: 2016-05-03
- Inventor: Francesco G. Salituro , Jeffrey O. Saunders
- Applicant: Francesco G. Salituro , Jeffrey O. Saunders
- Applicant Address: US MA Cambridge
- Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi, LLP
- International Application: PCT/US2011/066595 WO 20111221
- International Announcement: WO2012/088314 WO 20120628
- Main IPC: C07D265/36
- IPC: C07D265/36 ; C07D265/18 ; C07D413/12
Abstract:
Compounds and compositions comprising compounds that activate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that activate PKM2 in the treatment of cancer.
Public/Granted literature
- US20140011804A1 BICYCLIC PKM2 ACTIVATORS Public/Granted day:2014-01-09
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