Invention Grant
- Patent Title: Benzofurazan anti-amyloid compounds and methods
- Patent Title (中): 苯并呋咱抗淀粉样化合物及方法
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Application No.: US14422669Application Date: 2013-08-22
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Publication No.: US09328078B2Publication Date: 2016-05-03
- Inventor: Mark A Reed , Thomas K Wood , Scott C Banfield , Christopher J Barden
- Applicant: Treventis Corporation
- Applicant Address: US PA Bryn Mawr
- Assignee: Treventis Corporation
- Current Assignee: Treventis Corporation
- Current Assignee Address: US PA Bryn Mawr
- Agency: Davidson, Davidson & Kappel LLC
- International Application: PCT/US2013/056220 WO 20130822
- International Announcement: WO2014/031873 WO 20140227
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D413/12 ; C07D413/04 ; C07D417/12 ; C07D271/12 ; H02G3/38 ; F16L9/19 ; F16L11/20 ; F16L53/00 ; E21B36/00 ; E21B36/04

Abstract:
In general, among other things, compounds of Formula I are provided: in which R11 is selected from the group consisting of benzylamino, N-methylbenzylamino, morpholino, thiomorpholino, pyrrolidino, etc.; R13 is selected from the group consisting of 3-(1-ethanol-2-yl)phenyl, 3-(1-ol-2,2,2-trifluoroethan-2-yl)phenyl, 2-(1-ol-2,2,2-trifluoroethan-2-yl)phenyl, etc.; and R12 and R14 are each independently hydrogen or alkyl. Methods of treatment are also provided.
Public/Granted literature
- US20150266838A1 BENZOFURAZAN ANTI-AMYLOID COMPOUNDS AND METHODS Public/Granted day:2015-09-24
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