Invention Grant
- Patent Title: Cyanomethylpyrazole carboxamides as janus kinase inhibitors
- Patent Title (中): 氰基甲基吡唑甲酰胺作为甘蔗激酶抑制剂
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Application No.: US14345978Application Date: 2012-09-21
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Publication No.: US09328099B2Publication Date: 2016-05-03
- Inventor: Jason Brubaker , Matthew Lloyd Childers , Matthew Christopher , Joshua T. Close , Jason David Katz , Joon Jung , Scott Peterson , Phieng Siliphaivanh , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Hongjun Zhang
- Applicant: Jason Brubaker , Matthew Lloyd Childers , Matthew Christopher , Joshua T. Close , Jason David Katz , Joon Jung , Scott Peterson , Phieng Siliphaivanh , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Hongjun Zhang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Catherine D. Fitch
- International Application: PCT/US2012/056478 WO 20120921
- International Announcement: WO2013/043962 WO 20130328
- Main IPC: C07D231/38
- IPC: C07D231/38 ; C07D405/04 ; C07D401/14 ; C07D401/04 ; C07D403/04 ; C07D405/08 ; C07D403/12 ; C07D401/12 ; C07D403/08 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D401/06 ; C07D403/06 ; C07D405/06 ; C07D405/14 ; C07D409/04 ; C07D413/14 ; C07D417/14
Abstract:
The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
Public/Granted literature
- US20140228348A1 CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS Public/Granted day:2014-08-14
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