Invention Grant
- Patent Title: Compounds and methods for regulating integrins
- Patent Title (中): 调节整合素的化合物和方法
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Application No.: US14517667Application Date: 2014-10-17
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Publication No.: US09328105B2Publication Date: 2016-05-03
- Inventor: Vineet Gupta
- Applicant: ADHAERE PHARMACEUTICALS, INC.
- Applicant Address: US IL Skokie
- Assignee: ADHAERE PHARMACEUTICALS, INC.
- Current Assignee: ADHAERE PHARMACEUTICALS, INC.
- Current Assignee Address: US IL Skokie
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61N5/10
- IPC: A61N5/10 ; A61K31/337 ; A61K31/427 ; C07D417/06 ; A61K45/06 ; A61K31/5377 ; C07D417/14
Abstract:
A method of treating inflammation, by administering an effective amount of a β2 integrin agonist to a patient, and reducing inflammation. A method of treating cancer, by administering an effective amount of a β2 integrin agonist to a patient, and reducing tumor growth. A method of treating a patient exposed to radiation, by administering an effective amount of a β2 integrin agonist to the patient after radiation exposure, and mitigating the effects of radiation exposure in the patient. A method of preventing effects of radiation, by administering an effective amount of a β2 integrin agonist to the patient prior to radiation exposure, and preventing the effects of radiation exposure on the patient. A method of treating acquired bone marrow failure (BMF), by administering an effective amount of a β2 integrin agonist to a patient. Methods of improving the health of damaged vasculature in a patient and activating β2 integrins.
Public/Granted literature
- US20150105435A1 COMPOUNDS AND METHODS FOR REGULATING INTEGRINS Public/Granted day:2015-04-16
Information query
