Invention Grant
- Patent Title: Diazole lactams
- Patent Title (中): 二唑内酰胺
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Application No.: US14099541Application Date: 2013-12-06
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Publication No.: US09328116B2Publication Date: 2016-05-03
- Inventor: Xi Chen , Pingchen Fan , Yandong Li , Jay P. Powers , Viengkham Malathong , Sreenivas Punna , Hiroko Tanaka , Penglie Zhang , Dean Dragoli
- Applicant: ChemoCentryx, Inc.
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61K31/4196 ; A61K31/4155 ; C07D487/04 ; A61K45/06 ; C07D401/14 ; C07D403/14 ; C07D405/14 ; C07D471/04
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20140171420A1 DIAZOLE LACTAMS Public/Granted day:2014-06-19
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