Invention Grant
- Patent Title: Peptidomimetic inhibitors of PSMA
- Patent Title (中): PSMA的拟肽抑制剂
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Application No.: US13884394Application Date: 2011-11-10
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Publication No.: US09328129B2Publication Date: 2016-05-03
- Inventor: Clifford E. Berkman , Henry F. Vanbrocklin
- Applicant: Clifford E. Berkman , Henry F. Vanbrocklin
- Applicant Address: US WA Pullman US CA Oakland
- Assignee: Washington State University,The Regents of the University of California
- Current Assignee: Washington State University,The Regents of the University of California
- Current Assignee Address: US WA Pullman US CA Oakland
- Agency: Whitman, Curtis, Christofferson & Cook, P.C.
- International Application: PCT/US2011/060088 WO 20111110
- International Announcement: WO2012/064914 WO 20120518
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; C07F9/24 ; A61K31/664 ; A61K51/04 ; C07F13/00 ; G01N33/574

Abstract:
Compounds of the formulae, (I), wherein each variable is as defined herein are provided which are useful in (i) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable carrier, excipient, and/or diluent; (3) methods for inhibiting or treating prostrate cancer; and (4) methods for blocking or destabilizing neovasculature of a tumor.
Public/Granted literature
- US20140010758A1 PEPTIDOMIMETIC INHIBITORS OF PSMA Public/Granted day:2014-01-09
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