Invention Grant
- Patent Title: Lipopeptide inhibitors of RAS oncoproteins
- Patent Title (中): RAS癌蛋白的脂肽抑制剂
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Application No.: US14119596Application Date: 2012-05-25
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Publication No.: US09328142B2Publication Date: 2016-05-03
- Inventor: Nadya I. Tarasova , Sergey G. Tarasov , Vadim Gaponenko , Joseph Kates , Alla Ivanova , Michael C. Dean
- Applicant: Nadya I. Tarasova , Sergey G. Tarasov , Vadim Gaponenko , Joseph Kates , Alla Ivanova , Michael C. Dean
- Applicant Address: US DC Washington US WA Kirkland CA Vancouver US TN Nashville US IL Urbana
- Assignee: The United States of America, as represented by The Secretary, Department of Health and Human Services,Joseph Robert Kates,Yin Hwee Tan,Vanderbilt University,The Board of Trustees of the University of Illinois
- Current Assignee: The United States of America, as represented by The Secretary, Department of Health and Human Services,Joseph Robert Kates,Yin Hwee Tan,Vanderbilt University,The Board of Trustees of the University of Illinois
- Current Assignee Address: US DC Washington US WA Kirkland CA Vancouver US TN Nashville US IL Urbana
- Agency: Leydig, Voit & Mayer, LTD.
- International Application: PCT/US2012/039623 WO 20120525
- International Announcement: WO2012/162628 WO 20121129
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K7/06 ; C07K14/82
Abstract:
The invention provides a peptide or peptidomimetic that is derived from or based upon the amino acid sequence of the C-terminal α-helix or hypervariable region (HVR) or a Ras protein, a nucleic acid encoding the peptide or peptidomimetic, and methods employing the same.
Public/Granted literature
- US20140135276A1 LIPOPEPTIDE INHIBITORS OF RAS ONCOPROTEINS Public/Granted day:2014-05-15
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