Invention Grant
US09328143B2 Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
有权
肽衍生物及其作为缀合物形式的分子的载体的用途
- Patent Title: Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
- Patent Title (中): 肽衍生物及其作为缀合物形式的分子的载体的用途
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Application No.: US14277339Application Date: 2014-05-14
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Publication No.: US09328143B2Publication Date: 2016-05-03
- Inventor: Michel Khrestchatisky , Marion David , Yves Molino , Patrick Vlieghe
- Applicant: VECT-HORUS , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE D'AIX MARSEILLE
- Applicant Address: FR Marseilles FR Paris FR Marseilles
- Assignee: VECT-HORUS,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE DE LA MEDITERRANEE (AIX MARSEILLE II)
- Current Assignee: VECT-HORUS,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE DE LA MEDITERRANEE (AIX MARSEILLE II)
- Current Assignee Address: FR Marseilles FR Paris FR Marseilles
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: FR0857159 20081022
- Main IPC: C07K7/64
- IPC: C07K7/64 ; A61K38/12 ; C07K7/08 ; C07K14/775 ; C07K4/00 ; C07K7/06 ; C07K14/00 ; A61K38/00
Abstract:
The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorize molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
Public/Granted literature
- US20140243499A1 PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES Public/Granted day:2014-08-28
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