Invention Grant
- Patent Title: Anti-nerve growth factor antibodies and methods of preparing and using the same
- Patent Title (中): 抗神经生长因子抗体及其制备及使用方法
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Application No.: US14115787Application Date: 2012-05-08
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Publication No.: US09328164B2Publication Date: 2016-05-03
- Inventor: David Gearing
- Applicant: David Gearing
- Applicant Address: AU Melbourne
- Assignee: NVIP PTY LTD
- Current Assignee: NVIP PTY LTD
- Current Assignee Address: AU Melbourne
- Agency: Foley & Lardner LLP
- International Application: PCT/GB2012/051003 WO 20120508
- International Announcement: WO2012/153122 WO 20121115
- Main IPC: C07K16/22
- IPC: C07K16/22 ; C07K16/46
Abstract:
A method of preparing an antibody suitable for use in a feline is provided. Also provided are chimeric and felinized antibodies which specifically bind to feline neuronal growth factor (NGF) and neutralize the ability of feline NGF to bind to the p75 or TrkA feline NGF receptor. The invention extends to nucleic acids encoding same and to methods of treating pain and arthritis in a feline using said antibodies and/or nucleic acids.
Public/Granted literature
- US20140147439A1 ANTI-NERVE GROWTH FACTOR ANTIBODIES AND METHODS OF PREPARING AND USING THE SAME Public/Granted day:2014-05-29
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