Invention Grant
- Patent Title: Antibodies directed against IL-17
- Patent Title (中): 针对IL-17的抗体
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Application No.: US13814262Application Date: 2011-08-02
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Publication No.: US09328166B2Publication Date: 2016-05-03
- Inventor: Robert Horlick , David King , Peter Bowers , Jennifer Dalton , Betty Wu , Traci Roberts , Xue Zhang , Laurence Altobell, III
- Applicant: Robert Horlick , David King , Peter Bowers , Jennifer Dalton , Betty Wu , Traci Roberts , Xue Zhang , Laurence Altobell, III
- Applicant Address: US CA San Diego
- Assignee: AnaptysBio, Inc.
- Current Assignee: AnaptysBio, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2011/046201 WO 20110802
- International Announcement: WO2012/018767 WO 20120209
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61K39/00
Abstract:
The invention relates to an isolated interleukin-17 (IL-17)-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 78, or SEQ ID NO: 79, and an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The invention also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.
Public/Granted literature
- US20130202591A1 ANTIBODIES DIRECTED AGAINST IL-17 Public/Granted day:2013-08-08
Information query
