Invention Grant
- Patent Title: Chemokine receptor binding polypeptides
- Patent Title (中): 趋化因子受体结合多肽
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Application No.: US13886530Application Date: 2013-05-03
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Publication No.: US09328174B2Publication Date: 2016-05-03
- Inventor: Zarin Brown , Michelle Bradley , Steven John Charlton , Gino Anselmus Van Heeke , Karen Cromie , Bruno Dombrecht , Soren Steffensen , Judith Baumeister , Marie-Paule Bouche , Carlo Boutton , Marie-Ange Buyse , Veerle Snoeck , Stephanie Staelens
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/28

Abstract:
The present invention relates to polypeptides directed against or specifically binding to CXC chemokine receptor 2 (“CXCR2”) and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.
Public/Granted literature
- US20130330346A1 Chemokine receptor binding polypeptides Public/Granted day:2013-12-12
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