Invention Grant
US09328378B2 Method of library preparation avoiding the formation of adaptor dimers
有权
图书馆准备方法避免形成适配器二聚体
- Patent Title: Method of library preparation avoiding the formation of adaptor dimers
- Patent Title (中): 图书馆准备方法避免形成适配器二聚体
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Application No.: US12309772Application Date: 2007-07-30
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Publication No.: US09328378B2Publication Date: 2016-05-03
- Inventor: David James Earnshaw , Niall Anthony Gormley , Helen Rachel Bignell , Melanie Anne Smith
- Applicant: David James Earnshaw , Niall Anthony Gormley , Helen Rachel Bignell , Melanie Anne Smith
- Applicant Address: GB Nr Saffron Walden
- Assignee: Illumina Cambridge Limited
- Current Assignee: Illumina Cambridge Limited
- Current Assignee Address: GB Nr Saffron Walden
- Agency: Illumina, Inc.
- Agent Brent C. Moore
- International Application: PCT/GB2007/002865 WO 20070730
- International Announcement: WO2008/015396 WO 20080207
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The invention relates to a method of preparing a library of template polynucleotides which reduces and/or prevents the formation of adaptor-dimers. The invention also relates to the use of a library of templates prepared using the method of the invention for solid-phase nucleic acid amplification. In particular, the invention relates to a method of preparing a library of template polynucleotides which have common sequences at their 5′ ends and at their 3′ ends which is substantially free of adaptor-dimers.
Public/Granted literature
- US20100167954A1 METHOD OF LIBRARY PREPARATION AVOIDING THE FORMATION OF ADAPTOR DIMERS Public/Granted day:2010-07-01
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