Invention Grant
US09329170B2 Single cell gene expression for diagnosis, prognosis and identification of drug targets
有权
单细胞基因表达用于诊断，预后和鉴定药物靶标
- Patent Title: Single cell gene expression for diagnosis, prognosis and identification of drug targets
- Patent Title (中): 单细胞基因表达用于诊断，预后和鉴定药物靶标
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Application No.: US12657457Application Date: 2010-01-20
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Publication No.: US09329170B2Publication Date: 2016-05-03
- Inventor: Michael F. Clarke , Stephen R. Quake , Piero D. Dalerba , Huiping Liu , Anne Leyrat , Tomer Kalisky , Maximilian Diehn , Jianbin Wang
- Applicant: Michael F. Clarke , Stephen R. Quake , Piero D. Dalerba , Huiping Liu , Anne Leyrat , Tomer Kalisky , Maximilian Diehn , Jianbin Wang
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: G01N33/50
- IPC: G01N33/50 ; C12Q1/68
Abstract:
Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.
Public/Granted literature
- US20100255471A1 Single cell gene expression for diagnosis, prognosis and identification of drug targets Public/Granted day:2010-10-07
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