Invention Grant
- Patent Title: Mechanically induced trapping of molecular interactions
- Patent Title (中): 机械诱导分子相互作用的捕获
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Application No.: US13317063Application Date: 2011-10-06
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Publication No.: US09329179B2Publication Date: 2016-05-03
- Inventor: Stephen R. Quake , Sebastian J. Maerkl
- Applicant: Stephen R. Quake , Sebastian J. Maerkl
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: G01N33/563
- IPC: G01N33/563 ; G01N33/543 ; G01N33/53 ; B01L3/00
Abstract:
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.
Public/Granted literature
- US20120129719A1 Mechanically induced trapping of molecular interactions Public/Granted day:2012-05-24
Information query
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