A color filter substrate, a display panel and a display device are provided. The color filter substrate includes a first substrate, a black matrix layer located on the first substrate, and an electrostatic discharge wire layer located on the black matrix layer and connected to the black matrix layer. In the color filter substrate, the display panel and the display device, the electrostatic discharge wire layer is arranged on the black matrix layer of the color filter substrate. Hence, static electricity in the color filter substrate is discharged via the electrostatic discharge wire layer, and accordingly, the static electricity may not be accumulated in the color filter substrate, thereby improving the quality and performance of a display.