Invention Grant
- Patent Title: Amphiphilic compound assisted nanoparticles for targeted delivery
- Patent Title (中): 两亲化合物辅助纳米颗粒用于靶向递送
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Application No.: US12573591Application Date: 2009-10-05
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Publication No.: US09333179B2Publication Date: 2016-05-10
- Inventor: Liangfang Zhang , Aleksandar F. Radovic-Moreno , Frank X. Gu , Frank Alexis , Robert S. Langer , Omid C. Farokhzad
- Applicant: Liangfang Zhang , Aleksandar F. Radovic-Moreno , Frank X. Gu , Frank Alexis , Robert S. Langer , Omid C. Farokhzad
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: Massachusetts Institute of Technology,The Brigham and Women's Hospital, Inc.
- Current Assignee: Massachusetts Institute of Technology,The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Pabst Patent Group LLP
- Main IPC: A61K9/51
- IPC: A61K9/51 ; A61K47/48 ; B82Y5/00
Abstract:
The present invention generally relates to nanoparticles with an amphiphilic component. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.
Public/Granted literature
- US20100203142A1 AMPHIPHILIC COMPOUND ASSISTED NANOPARTICLES FOR TARGETED DELIVERY Public/Granted day:2010-08-12
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