Invention Grant
US09333199B2 Methods of treatment of histamine H-4 receptor-related pruritus associated with nerve disorders 有权
治疗与神经障碍相关的组胺H-4受体相关性瘙痒的方法

Methods of treatment of histamine H-4 receptor-related pruritus associated with nerve disorders
Abstract:
The methods disclosed herein relate to the treatment of histamine H-4-related pruritus associated with nerve disorders, by administering a combined histamine H-1 and H-4 receptor inhibitor, specifically RS-norketotifen or a pharmaceutically acceptable salt thereof. Potentiated antipruritic activity by simultaneous inhibition of histamine H-1 receptors and histamine H-4 receptors are described.
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