Invention Grant
- Patent Title: FGFR1 antibodies and treatment of cancer
- Patent Title (中): FGFR1抗体和癌症治疗
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Application No.: US14004913Application Date: 2012-03-14
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Publication No.: US09333257B2Publication Date: 2016-05-10
- Inventor: Simon Cool , Victor Nurcombe , Ling Ling
- Applicant: Simon Cool , Victor Nurcombe , Ling Ling
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Choate, Hall & Stewart LLP
- Agent Charles E. Lyon; Michael L. Vetter
- Priority: SG201103325 20110510
- International Application: PCT/SG2012/000085 WO 20120314
- International Announcement: WO2012/125124 WO 20120920
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28

Abstract:
The use of an FGFR1 antibody in the treatment of cancer is disclosed, wherein the FGFR1 antibody binds FGFR1 at an epitope that is positioned in the FGFR1 primary amino acid sequence no more than 50 contiguous amino acids away from the C- or N-terminal of the FGFR1 heparin binding domain.
Public/Granted literature
- US20140086925A1 FGFR1 ANTIBODIES AND TREATMENT OF CANCER Public/Granted day:2014-03-27
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