Invention Grant
US09334276B2 Forms and salts of a dihydropyrrolo[1,2c]imidazolyl aldosterone synthase or aromatase inhibitor 有权
二氢吡咯并[1,2c]咪唑基醛固酮合酶或芳香酶抑制剂的形式和盐

  • Patent Title: Forms and salts of a dihydropyrrolo[1,2c]imidazolyl aldosterone synthase or aromatase inhibitor
  • Patent Title (中): 二氢吡咯并[1,2c]咪唑基醛固酮合酶或芳香酶抑制剂的形式和盐
  • Application No.: US14370124
    Application Date: 2013-01-15
  • Publication No.: US09334276B2
    Publication Date: 2016-05-10
  • Inventor: Paul Allen SuttonEric Loeser
  • Applicant: Novartis AG
  • Applicant Address: CH Basel
  • Assignee: Novartis AG
  • Current Assignee: Novartis AG
  • Current Assignee Address: CH Basel
  • Agent Michelle Han
  • International Application: PCT/US2013/021521 WO 20130115
  • International Announcement: WO2013/109514 WO 20130725
  • Main IPC: C07D487/04
  • IPC: C07D487/04
Forms and salts of a dihydropyrrolo[1,2c]imidazolyl aldosterone synthase or aromatase inhibitor
Abstract:
The invention relates to a phosphate salt or a nitrate salt of 4-(R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl-3-fluoro-benzonitrile, especially in crystalline form, and specific forms of these salts, as well as related invention embodiments. The salts and salt forms allow for the prophylactic and/or therapeutic treatment of aldosterone synthase and/or aromatase mediated diseases or disorders.
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