Invention Grant
US09334300B2 Vitamin B6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates
有权
维生素B6衍生物的核苷酸，非循环核苷酸和非循环核苷酸膦酸酯
- Patent Title: Vitamin B6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates
- Patent Title (中): 维生素B6衍生物的核苷酸，非循环核苷酸和非循环核苷酸膦酸酯
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Application No.: US14236178Application Date: 2012-08-01
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Publication No.: US09334300B2Publication Date: 2016-05-10
- Inventor: Alexander Karpeisky , Shawn Zinnen , Murali Urlam , Vladimir Y. Vvedensky , Andrei P. Guzaev
- Applicant: Alexander Karpeisky , Shawn Zinnen , Murali Urlam , Vladimir Y. Vvedensky , Andrei P. Guzaev
- Applicant Address: US CO Aurora
- Assignee: MBC PHARMA, INC.
- Current Assignee: MBC PHARMA, INC.
- Current Assignee Address: US CO Aurora
- Agency: Brownstein Hyatt Farber Schreck LLP
- Agent Paul J. Prendergast; Cara Crowley-Weber
- International Application: PCT/US2012/049181 WO 20120801
- International Announcement: WO2013/019874 WO 20130207
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A01N43/04 ; C12N5/00 ; C12N5/02 ; C07H19/048 ; C07H19/10 ; C07D213/76 ; C07D213/65 ; C07H19/12 ; C07H19/20 ; C07H19/23 ; C07H19/19
Abstract:
Compounds and compositions are provided, as are methods of using them to treat infections, neoplastic disease, including pancreatic cancer, inflammatory disease, and pain. Such compounds are nucleotides, acyclonucleotides, and ANP phosphonates conjugated with forms and/or moieties of Vitamin B6 for delivery past the cell membrane and into the cell.
Public/Granted literature
- US20140329768A1 VITAMIN B6 DERIVATIVES OF NUCLEOTIDES, ACYCLONUCLEOTIDES AND ACYCLONUCLEOSIDE PHOSPHONATES Public/Granted day:2014-11-06
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