Invention Grant
- Patent Title: Hybrid polyketide synthases
- Patent Title (中): 混合聚酮化合物合成酶
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Application No.: US13882099Application Date: 2011-10-31
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Publication No.: US09334514B2Publication Date: 2016-05-10
- Inventor: Jeffrey L. Fortman , Andrew Hagen , Leonard Katz , Jay D. Keasling , Sean Poust , Jingwei Zhang , Sergey Zotchev
- Applicant: Jeffrey L. Fortman , Andrew Hagen , Leonard Katz , Jay D. Keasling , Sean Poust , Jingwei Zhang , Sergey Zotchev
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2011/058660 WO 20111031
- International Announcement: WO2012/058686 WO 20120503
- Main IPC: C12P17/18
- IPC: C12P17/18 ; C12P7/44 ; C12P7/46 ; C12P13/00 ; C12P13/04 ; C12N15/52 ; C12P17/10
Abstract:
The present invention provides for a polyketide synthase (PKS) capable of synthesizing an even-chain or odd-chain diacid or lactam or diamine. The present invention also provides for a host cell comprising the PKS and when cultured produces the even-chain diacid, odd-chain diacid, or KAPA. The present invention also provides for a host cell comprising the PKS capable of synthesizing a pimelic acid or KAPA, and when cultured produces biotin.
Public/Granted literature
- US20130280766A1 HYBRID POLYKETIDE SYNTHASES Public/Granted day:2013-10-24
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