The present invention provides a suspension and vibration isolation system having cable isolators. The cable isolators employ low-friction air-bearing pneumatic cylinders and cables to isolate a suspended payload from vibrations of a carrier or to isolate the carrier from vibrations of the payload. Using such air-lubricated cylinder to piston interfaces virtually eliminates static friction and so improves the effectiveness of the isolation for small forces and displacement. The use of pneumatic cylinders also permits the system to be tuned to the required resonance frequency to isolate the payload from vibrations in a desired frequency band.