An air-conditioning apparatus once transfers energy to a heat medium other than a refrigerant and introduces the heat medium to another refrigeration cycle to achieve safety improvement and high efficiency. An air-conditioning apparatus allows first heat exchangers related to heat medium to exchange heat between a first refrigerant (heat source side refrigerant) and a first heat medium and allows a second heat exchanger related to heat medium to exchange heat between the first heat medium and a second refrigerant (hot water supply side refrigerant), such that the first refrigerant and the second refrigerant are prevented from mixing with each other.