Invention Grant
- Patent Title: Process for preparing a medicament
- Patent Title (中): 制备药物的方法
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Application No.: US10594473Application Date: 2004-09-01
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Publication No.: US09345664B2Publication Date: 2016-05-24
- Inventor: Xian-Ming Zeng , Sean Kee Tee
- Applicant: Xian-Ming Zeng , Sean Kee Tee
- Applicant Address: GB
- Assignee: NORTON HEALTHCARE LTD
- Current Assignee: NORTON HEALTHCARE LTD
- Current Assignee Address: GB
- Agency: RatnerPrestia
- International Application: PCT/US2004/028345 WO 20040901
- International Announcement: WO2005/020963 WO 20050310
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K31/58 ; A61M15/00 ; A61K9/00 ; A61K31/137 ; A61K31/167

Abstract:
The present invention provides a process for preparing a particulate medicament that has greater homogeneity and a lower adhesion between the particles of the active ingredient and the carrier. The process comprises the steps of: (a) combining a pharmaceutically active ingredient in the form of an agglomerate of primary particles having an agglomerate particle size such that the agglomerate is capable of passing through a sieve having a mesh of 50-3000 μm with a pharmaceutically acceptable particulate carrier, and (b) mixing the resultant material in a mixer to break up the agglomerate into primary particles dispersed in the pharmaceutically acceptable particulate carrier such that 90% or more of the pharmaceutically active ingredient exists as primary particles having a particle size of 50 μm or less.
Public/Granted literature
- US20080131518A1 Process for Preparing a Medicament Public/Granted day:2008-06-05
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