Invention Grant
US09345692B2 Pharmaceutical formulations: salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxy-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
有权
药物制剂:8- [1-3,5-双 - (三氟甲基)苯基) - 乙氧基 - 甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮的盐和使用 一样
- Patent Title: Pharmaceutical formulations: salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxy-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
- Patent Title (中): 药物制剂:8- [1-3,5-双 - (三氟甲基)苯基) - 乙氧基 - 甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮的盐和使用 一样
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Application No.: US13847242Application Date: 2013-03-19
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Publication No.: US09345692B2Publication Date: 2016-05-24
- Inventor: Zhihui Qiu , Larisa Reyderman
- Applicant: OPKO Health, Inc.
- Applicant Address: US FL Miami
- Assignee: OPKO Health, Inc.
- Current Assignee: OPKO Health, Inc.
- Current Assignee Address: US FL Miami
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; Kristen C. Buteau
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/435 ; A61K9/16 ; A61K9/48 ; A61K31/438
![Pharmaceutical formulations: salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxy-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same](/abs-image/US/2016/05/24/US09345692B2/abs.jpg.150x150.jpg)
Abstract:
Pharmaceutical formulations containing salts of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl]-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, are disclosed. Disclosed also are methods of treatment utilizing such dosage forms.
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