Invention Grant
US09345723B2 Rapid formation of chitosan sponges using guanosine 5′-diphosphate: injectable scaffolds for tissue regeneration and drug delivery
有权
使用鸟苷5'-二磷酸快速形成壳聚糖海绵:用于组织再生和药物递送的可注射支架
- Patent Title: Rapid formation of chitosan sponges using guanosine 5′-diphosphate: injectable scaffolds for tissue regeneration and drug delivery
- Patent Title (中): 使用鸟苷5'-二磷酸快速形成壳聚糖海绵:用于组织再生和药物递送的可注射支架
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Application No.: US14424643Application Date: 2013-09-04
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Publication No.: US09345723B2Publication Date: 2016-05-24
- Inventor: Mina Mekhail , Guillermina Almazan , Maryam Tabrizian
- Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
- Agency: Norton Rose Fulbright Canada LLP
- International Application: PCT/CA2013/050677 WO 20130904
- International Announcement: WO2014/036649 WO 20140313
- Main IPC: A61F2/02
- IPC: A61F2/02 ; A61K31/722 ; A61K9/16 ; A61L27/20 ; A61L27/52 ; C08K5/529 ; C08L5/08 ; A61L27/54 ; A61K9/00 ; C08B37/08 ; A61K31/713 ; A61K38/02 ; A61K38/18 ; A61K48/00 ; A61K47/26 ; A61K47/36

Abstract:
It is disclosed Guanosine 5′-Diphosphate (GDP) crosslinked chitosan sponge or gelling composition which is used as a scaffold for tissue regeneration applications such as neural, cardiac, cartilage and bone regeneration. In addition, the sponge acts as a drug delivery system to provide local controlled drug release, such as delivering anti-cancer drugs locally at the tumor site.
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