Invention Grant
US09345744B2 Peptide-based collagen modulators for wound healing and tissue repair
有权
用于伤口愈合和组织修复的基于肽的胶原调节剂
- Patent Title: Peptide-based collagen modulators for wound healing and tissue repair
- Patent Title (中): 用于伤口愈合和组织修复的基于肽的胶原调节剂
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Application No.: US14396571Application Date: 2013-04-25
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Publication No.: US09345744B2Publication Date: 2016-05-24
- Inventor: Robert G. Gourdie , Edie C. Goldsmith , L. Jane Jourdan , Joshua Matthew Rhett , Michael J. Yost
- Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT , UNIVERSITY OF SOUTH CAROLINA
- Applicant Address: US SC Charleston US SC Columbia
- Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT,UNIVERSITY OF SOUTH CAROLINA
- Current Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT,UNIVERSITY OF SOUTH CAROLINA
- Current Assignee Address: US SC Charleston US SC Columbia
- Agency: Parker Highlander PLLC
- International Application: PCT/US2013/038207 WO 20130425
- International Announcement: WO2013/163423 WO 20131031
- Main IPC: C07K7/06
- IPC: C07K7/06 ; C07K7/08 ; A61L27/22 ; A61L27/54 ; A61K38/08 ; A61K38/10 ; A61L27/34 ; A61L31/04 ; A61L31/10 ; A61L31/16 ; A61L15/32 ; A61L15/44 ; A61L17/00 ; A61K9/00 ; A61K47/10 ; C07K14/47 ; A61K45/06 ; A61K38/00
Abstract:
Provided are peptides that can inhibit collagen synthesis, processing and/or secretion from scar forming cells or fibroblasts. Also provided are methods for using the peptides to produce an anti-fibrotic, anti-scarring, anti-inflammatory, and/or pro-regenerative effect, e.g., on an injured or diseased tissue.
Public/Granted literature
- US20150174196A1 COMPOSITIONS AND METHODS FOR WOUND HEALING AND TISSUE REPAIR Public/Granted day:2015-06-25
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