Invention Grant
US09345776B2 Biodegradable polymers with sulfenamide bonds for drug delivery applications
有权
具有亚磺酰胺键的生物可降解聚合物用于药物递送应用
- Patent Title: Biodegradable polymers with sulfenamide bonds for drug delivery applications
- Patent Title (中): 具有亚磺酰胺键的生物可降解聚合物用于药物递送应用
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Application No.: US13984228Application Date: 2012-02-10
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Publication No.: US09345776B2Publication Date: 2016-05-24
- Inventor: Ned B. Bowden , Denison J. Kuruvilla , Aliasger K. Salem , Jun Yoo
- Applicant: Ned B. Bowden , Denison J. Kuruvilla , Aliasger K. Salem , Jun Yoo
- Applicant Address: US IA Iowa City
- Assignee: The University of Iowa Research Foundation
- Current Assignee: The University of Iowa Research Foundation
- Current Assignee Address: US IA Iowa City
- Agency: Klintworth and Rozenblat IP LLC
- International Application: PCT/US2012/024734 WO 20120210
- International Announcement: WO2012/115806 WO 20120830
- Main IPC: A61K47/34
- IPC: A61K47/34 ; C08G75/30 ; C08G73/00
Abstract:
The present invention provides methods for preparing polysulfenamides having a repeating unit of formula (4): wherein R1 is selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, ether, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl. Each of R4, R5 and R6 are independently selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, ether, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl. Microparticles comprising polysulfenamides can be used as delivery vehicles for a variety of biological applications.
Public/Granted literature
- US20140099506A1 Biodegradable Polymers with Sulfenamide Bonds for Drug Delivery Applications Public/Granted day:2014-04-10
Information query
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